agings

Attempts to define biological aging: scope, actionability, plurality

There are many ways to define biological/organismal aging, here I collected together 6. They are presented in historical order to show how different topics showed up in them and thinking on aging gained more depth. You should not expect strict definitions in the logical sense with necessary and sufficient conditions but attempts to highlight the […]

Cellular senescence: zombie cells and matrix metalloproteinases

In a recent Quartz piece called The first drugs designed to fight aging are ready for human testing, the journalist W. Harry Fortuna provides an excellent and pictorial description of the important biological process, cellular senescence: Senolytics target a known mechanism of aging, cell senescence. Normally, cells die a “complete” death known as apoptosis. Senescence is […]

Top 4 ‘getting started’ in aging & healthspan extension resources

During a recent Gen P user experience session one early adopter asked me to provide a reading list to get the user started with digging into understanding aging science and longevity and healthspan extension technologies/scenarios. Here I provide a short subjective list containing different resources suited to a general non-biomedical audience. The list contains 1 scientific […]

It’s agings, not just aging: how the AgeCurve kit covers separate underlying processes

For the sake of simplicity people use ‘Aging’ as a term to denote all the underlying processes behind this most complex biological phenomenon, experienced by most and happening in all human adults during their lifetime. Laypeople and scientists alike use the singular form, while in the light of recent research (think of the last couple decades) it’s […]